Faculty Interest
Barletta, R.G., rbarletta@unl.edu Molecular genetics of bacterial pathogenesis and drug resistance, with emphasis of mycobactrial infections of humans and animals (tuberculosis and paratuberculosis). Johne’s disease, inflammatory bowel disease and Mycobacterium paratuberculosis. Chacon, O., Bermudez, L.E., Barletta, R.G. 2004. Annu Rev Microbiol 58:329-63. Brodersen, B.W., bbrodersen1@unl.edu Further development of test methodologies for detection of cattle persistently infected with bovine viral diarrhea virus. Pathogenesis of bovine viral diarrhea virus infections. Immunohistochemistry used as a screening method for persistent bovine viral diarrhea virus infection. Brodersen, B.W. 2004. Vet Clin of North America: Food Animal Practice 20:85-93. Doster, A.R., adoster@unlnotes.unl.edu PRRS virus infection in swine and its effects on the host regarding variation in strains, host genetics, and latency. Additional studies are under way to study the effects of latency and reactivation of bovine herpesvirus 1 in cattle.Protection against Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection through passive transfer of PRRSV-neutralizing antibodies is dose dependent. Doster, A.R. 2007. Clin Vac Immunol 14:269-75. Duhamel, G.E., aduhamel1@unl.edu Molecular mechanisms of bacterial pathogenesis with practical applications to diagnosis and control of enteric diseases in human beings and animals caused by Brachyspira pilosicoli and enterohepatic Helicobacter species. Colonic spirochetosis of colony-raised rhesus macaques associated with Brachyspira and Helicobacter. Duhamel, G.E., Stryker, C.J., Lu, G., Wong, V.J., Tarara, R.P. 2003. Anaerobe 9:45-55. Griffin, D.D., dgriffin@gpvec.unl.edu Interrelationships of factors affecting grass and feeder cattle production. Assessing performance of feedlot operations using epidemiology. Corbin, M.J., Griffin, D. 2006. Vet Clin of North America 22:1:35-52. Jones, C., cjones@unlnotes.unl.edu Regulation of alpha-herpesvirus latency and neurovirulence, analysis of alpha-herpesvirus genes expressed during latency, innate immune response to virus infection, and regulation of apoptosis by herpesviruses. A protein encoded by the bovine herpes virus 1 (BHV-1) latency related gene interacts with specific cellular regulatory proteins, including the CCAAT enhancer binding protein alpha (C/EBP-). Meyer, F., Perez, S., Geiser, V., Sintek, M., Inman, M., Jones, C. 2007. J Virol 81:59-67. Kelling, C.L., ckelling1@unl.edu Pathogenesis and virulence of bovine viral diarrhea virus and bovine respiratory syncytial virus. In vitro and vivo translational efficiencies of the 5’ untranslated region from eight genotype 2 bovine viral diarrhea virus field isolates. Topliff, C.L., Chon, S.K., Donis, R.O., Eskridge, K.M., Kelling, C.L. 2005. Virology 331:349-356. Lou, M.F., mlou1@unl.edu Biochemical mechanism of age-related cataract, the redox regulation and signal transduction in ocular tissues. Control of PDGF-induced reactive oxygen species (ROS) generation and signal transduction in the human lens epithelial cells. Chen, C-W.K., Zhou, Y., Zhang, W., Lou, M.F. 2007. Molecular Vision 13:374-387. McVey, D.S., dmcvey2@unl.edu Molecular diagnostics and vaccinology associated with bacterial infections with emphasis on bovine respiratory disease and mastitis. Identification of multiple linear epitopes of the plasminogen activator A (PauA) of Streptococcus uberis with murine monoclonal antibodies. McVey, D.S., Shi, J., Leigh, J.A., Rosey, E.L., Ward, P.N., Field, R., Yancey, R.J. 2005. Vet Immuno Immunopath 104:155-162. Moxley, R.A., rmoxley1@unl.edu Pathogenesis of enterotoxigenic and enterohemorrhagic Escherichia coli infections in swine and cattle. Anti-capsular antibodies activate killing of Escherichia coli O8:K87 by the alternative complement pathway in porcine serum. Clark, N.M., Berberov, E.M., Wang, M., Moxley, R.A. 2006. Vet Immunol Immunopath 114:185-91. Osorio, F.A., fosorio1@unl.edu Virulence and pathogenesis of two major viral agents that affect swine: Pseudorabies Virus (a herpesvirus) and Porcine Reproductive and Respiratory Syndrome Virus (an arterivirus, ssRNA+ genome). Serologic marker candidates identified amongst B-cell linear epitopes of Nsp2 and structural proteins of a North American Strain of Porcine Reproductive and Respiratory Syndrome virus. 2006. DeLima, M., Pattnaik, A.K., Flores, E.F., Osorio, F.A. Virology 353:410-421 Pattnaik, A., apattnaik2@unl.edu Molecular mechanisms of RNA virus transcription, replication, and assembly; viral pathogenesis; attenuated viruses and vaccines. Visualization of intracellular transport of vesicular stomatitis virus nucleocapsids in living cells. Das, S.C., Nayak, D., Zhou, Y., Pattnaik, A.K. 2006. J Virol 80:6368-77. Reddy, Jay, nreddy2@unl.edu Rogers, D.G. Pathogenesis of bacterial infections in livestock. Effects of Moraxella (Branhamella) ovis culture filtrates on bovine erythrocytes, peripheral blood mononuclear cells and corneal epithelial cells. Cerny, H.E., Rogers, D.G. 2006. J Clinical Microbiology 144:772-776. Rupp, G., grupp@gpvec.unl.edu Reproduction, nutrition, management and economic aspects of beef cattle production. Localization of period 1 mRNA in the ruminant oocyte and investigations of its role in ovarian function. Cushman, R.A., Allan, M.F., Jones, S.A., Rupp, G.P., Echternkamp, S.E. 2006. Animal Reproduction Science. (Submitted) Smith, D.R., dsmith8@unl.edu Managing cattle production systems to prevent disease, improve productivity, and protect public health; in particular the biosecurity and pathogen containment of bovine viral diarrhea, Johne’s disease, neonatal diarrhea, and food safety pathogens. Use of rope-devices to describe and explain the feedlot ecology of Escherichia coli O157:H7 by time and place. Smith, D.R., Moxley, R.A., Clowser, S.L., Folmer, J.D., Hinkley, S., Erickson, G.E., Klopfenstein, T.J. 2005. Foodborne Pathogens & Disease 2(1)50-60. Somerville, G.A., gsomerville3@unl.edu Elucidation of the mechanisms by which staphylococcal metabolism controls virulence and survival within a host. Staphylococcus epidermidis polysaccharide intercellular adhesion production significantly increases during tricarboxylic acid cycle stress. Vuong, C., Kidder, J.B., Jacobson, E.R., Otto, M., Proctor, R.A., Somerville, G.A. 2005. J Bact 187:2967-2973. Steffen, D.J., dsteffen1@unl.edu Pathology of genetic and infectious diseases. Characterization of protection from systemic infection and disease by use of a modified-live noncytopathic bovine viral diarrhea virus type 1 vaccine in experimentally infected calves. Kelling, C.L., Hunsaker, B.D., Steffen, D.J., Topliff, C.L., Abdelmagid, O.Y., Eskridge, K.M. 2005. Am J Vet Res 66(10):1785-91. |
