Rodney Moxley

Expertise

Dr. Rodney Moxley is a Charles Bessey Professor in the School of Veterinary Medicine and Biomedical Sciences at the University of Nebraska-Lincoln. He obtained his DVM in 1978 and his PhD in Pathology in 1983, both from the University of Missouri-Columbia, and was selected as an Honorary Member of the American College of Veterinary Microbiologists in 2019.

Teaching

Dr. Moxley teaches VMED 642 Veterinary General, Cellular and Molecular Pathology. This is a course in the Professional Program in Veterinary Medicine with Iowa State University taken by second-semester VM1 students.

Research

Dr. Moxley is the Project Director of the Shiga toxin-producing Escherichia coli (STEC) Coordinated Agricultural Project (STEC-CAP) funded by the U.S. Department of Agriculture, National Institute of Food and Agriculture which has a long-term goal to reduce the occurrence and public health risks from STEC O26, O45, O103, O111, O121, O145, and O157:H7 in beef using a quantitative microbial risk assessment platform. Research in his laboratory addresses the detection, prevention and control of STEC in cattle and beef. He also has projects that focus on the pathogenesis of enterotoxigenic E. coli (ETEC) infections of swine.

Recent Publications

1. Stromberg, Z. R., G. L. Lewis, S. S. Aly, T. W. Lehenbauer, J. M. Bosilevac, N. Cernicchiaro, and R. A. Moxley. 2016. Prevalence and level of enterohemorrhagic Escherichia coli in culled dairy cows at harvest. Journal of Food Protection 79:421-431.
2. Chopyk, J., R. M. Moore, Z. DiSpirito, Z. R. Stromberg, G. L. Lewis, D. G. Renter, N. Cernicchiaro, R. A. Moxley, and K. E. Wommack. 2016. Presence of pathogenic Escherichia coli is correlated with bacterial community diversity and composition on pre-harvest cattle hides. Microbiome 4:9.
3. Stromberg, Z. R., G. L. Lewis, and R. A. Moxley. 2016. Comparison of agar media for the detection and quantification of Shiga toxin-producing Escherichia coli in cattle feces. Journal of Food Protection 79:939-949.
4. Stromberg, L. R., N. W. Hengartner, K. L. Swingle, R. A. Moxley, S. W. Graves, G. A. Montaño, and H. Mukundan. 2016. Membrane insertion for the detection of lipopolysaccharides: exploring the dynamics of amphiphile-in-lipid assays. PLoS One 11(5):e0156295.
5. Woods, T. A., H. M. Mendez, S. Ortega, X. Shi, D. Marx, J. Bai, R. A. Moxley, T. G. Nagaraja, S. Graves, and A. Deshpande. 2016. Development of 11-plex MOL-PCR assay for the rapid screening of samples for Shiga toxin-producing Escherichia coli. Frontiers in Cellular and Infection Microbiology 6:92.
6. Moxley, R. A., D. H. Francis, M. Tamura, D. B. Marx, K. Santiago-Mateo, and M. Zhao. 2017. Efficacy of urtoxazumab (TMA-15 humanized monoclonal antibody specific for Shiga toxin-2) against post-diarrheal sequelae caused by Escherichia coli O157:H7 infection in the gnotobiotic piglet model. Toxins 9:49.
7. Schneider, L. G., T. J. Klopfenstein, Z. R. Stromberg, G. L. Lewis, G. E. Erickson, R. A. Moxley, and D. R. Smith. 2018. A randomized controlled trial to evaluate the effects of dietary fibre from distillers grains on enterohemorrhagic Escherichia coli detection from the rectoanal mucosa and hides of feedlot steers. Zoonoses and Public Health 65:124-133
8. Stromberg, Z. R., G. L. Lewis, L. G. Schneider, G. E. Erickson, I. R. Patel, D. R. Smith, and R. A. Moxley. 2018. Culture-based quantification with molecular characterization of non-O157 and O157 enterohemorrhagic Escherichia coli isolates from rectoanal mucosal swabs of feedlot cattle. Foodborne Pathogens and Disease 15:26-32.
9. Kittana, H., M. I. Quintero-Villegas, L. B. Bindels, J. C. Gomes-Neto, R. J. Schmaltz, R. R. Segura Munoz, E. A. Cody, R. A. Moxley, J. Hostetter, R. W. Hutkins, and A. E. Ramer-Tait. 2018. Galactooligosaccharide supplementation provides protection against Citrobacter rodentium infection but does not limit pathogen adherence. Microbiology 164:154-162.
10. Lewis, G. L., Q. R. Jorgensen, J. D. Loy, and R. A. Moxley. 2018. Tellurite resistance in Shiga toxin-producing Escherichia coli. Current Microbiology 75:752-759.
11. Schneider, L. G., G. L. Lewis, R. A. Moxley, and D. R. Smith. 2018. A four-season longitudinal study of enterohemorrhagic Escherichia coli in beef cow-calf herds in Mississippi and Nebraska. Zoonoses and Public Health 65:552-559.
12. Schneider, L. G., Z. R. Stromberg, G. L. Lewis, R. A. Moxley, and D. R. Smith. 2018. Cross-sectional study to estimate the prevalence of enterohemorrhagic Escherichia coli on hides of market beef cows at harvest. Zoonoses and Public Health 65:625-636.
13. Lu, T., H. Seo, R. A. Moxley, and W. Zhang. 2019. Mapping the neutralizing epitopes of F18 fimbrial adhesin subunit FedF of enterotoxigenic Escherichia coli (ETEC). Veterinary Microbiology 230:171-177.
14. Lu, T., R. A. Moxley, and W. Zhang. 2019. Mapping the neutralizing epitopes of enterotoxigenic Escherichia coli (ETEC) K88 (F4) fimbrial adhesin and major subunit FaeG. Applied and Environmental Microbiology 85:e00329-19.
15. Moxley, R. A., D. R. Smith, D. M. Grotelueschen, and T. Edwards. 2019. Investigation of congestive heart failure in beef cattle in a feedyard at a moderate altitude in western Nebraska. Journal of Veterinary Diagnostic Investigation 31:509-522.
16. Moxley, R. A., T. W. Bargar, S. D. Kachman, D. R. Baker, and D. H. Francis. 2020. Intimate attachment of Escherichia coli O157:H7 to urinary bladder epithelium in the gnotobiotic piglet model. Microorganisms 8:263.
17. Lu, T., R. A. Moxley, and W. Zhang. 2020. Application of a novel epitope and structure vaccinology-assisted fimbria-toxin multiepitope fusion antigen of enterotoxigenic Escherichia coli for multivalent vaccine development against porcine post-weaning diarrhea. Applied and Environmental Microbiology 86:e00274-20.
18. Lewis, G., N. Cernicchiaro, and R. A. Moxley. 2020. Performance of chromogenic agar media for isolation of Shiga toxin-producing Escherichia coli from ground beef. Journal of Food Protection 83:1149-1154.
19. Moxley R. A. 2021. (Editorial) Special Issue: Shiga toxin-producing Escherichia coli. Microorganisms 9:1.
20. Jung, Y., A. C. S. Porto-Fett, S. Parveen, J. Meredith, B. A. Shoyer, E. Henry, Z. Trauger, L. E. Shane, M. Osoria, J. Schwarz, C. Rupert, B. Chapman, R. A. Moxley, and J. B. Luchansky. 2021. Recovery rate of cells of the seven regulated serogroups of Shiga toxin-producing Escherichia coli from raw veal cutlets, ground veal, and ground beef from retail stores in the mid-Atlantic region of the United States. Journal of Food Protection 84:220-232.
21. Hinenoya, A., X.-P. Li, H. Wang, X. Zeng, O. Sahin, R. A. Moxley, C. M. Logue, B. Gillespie, S. Yamasaki, and J. Lin. 2021. Isolation and characterization of Escherichia albertii in poultry at the pre-harvest level. Zoonoses and Public Health 68:213-225.