Rodney Moxley

Dr. Rodney Moxley
Professor Emeritus

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Faculty Profile


  • D.V.M., University of Missouri-Columbia, 1978
  • Ph.D. in pathology, University of Missouri-Columbia, 1983

Professional Responsibilities and Activities

  • Teaching
    Dr. Moxley teaches the VMED 642 Veterinary General, Cellular and Molecular Pathology course in the UNL Professional Program in Veterinary Medicine (PPVM) with Iowa State University taken by second-semester VM1 students. In addition, he teaches a portion of the VMED 672 Veterinary Systemic Pathology course taken by first-semester VM2 students in the PPVM.
  • Research
    Dr. Moxley conducts research that focuses on the detection, prevention and control of Shiga toxin-producing Escherichia coli (STEC) in cattle and beef, the pathogenesis and control of enterotoxigenic E. coli (ETEC) infections of swine, and antimicrobial resistance mechanisms in Salmonella enterica, primarily in cattle. He is a member and former chair of the Advisory Council of the National Institute of Antimicrobial Resistance Research and Education.



  1. Stromberg, Z. R., G. L. Lewis, S. S. Aly, T. W. Lehenbauer, J. M. Bosilevac, N. Cernicchiaro, and R. A. Moxley. 2016. Prevalence and level of enterohemorrhagic Escherichia coli in culled dairy cows at harvest. Journal of Food Protection 79:421-431.
  2. Chopyk, J., R. M. Moore, Z. DiSpirito, Z. R. Stromberg, G. L. Lewis, D. G. Renter, N. Cernicchiaro, R. A. Moxley, and K. E. Wommack. 2016. Presence of pathogenic Escherichia coli is correlated with bacterial community diversity and composition on pre-harvest cattle hides. Microbiome 4:9.
  3. Stromberg, Z. R., G. L. Lewis, and R. A. Moxley. 2016. Comparison of agar media for the detection and quantification of Shiga toxin-producing Escherichia coli in cattle feces. Journal of Food Protection 79:939-949.
  4. Stromberg, L. R., N. W. Hengartner, K. L. Swingle, R. A. Moxley, S. W. Graves, G. A. Montaño, and H. Mukundan. 2016. Membrane insertion for the detection of lipopolysaccharides: exploring the dynamics of amphiphile-in-lipid assays. PLoS One 11(5):e0156295.
  5. Woods, T. A., H. M. Mendez, S. Ortega, X. Shi, D. Marx, J. Bai, R. A. Moxley, T. G. Nagaraja, S. Graves, and A. Deshpande. 2016. Development of 11-plex MOL-PCR assay for the rapid screening of samples for Shiga toxin-producing Escherichia coli. Frontiers in Cellular and Infection Microbiology 6:92.
  6. Moxley, R. A., D. H. Francis, M. Tamura, D. B. Marx, K. Santiago-Mateo, and M. Zhao. 2017. Efficacy of urtoxazumab (TMA-15 humanized monoclonal antibody specific for Shiga toxin-2) against post-diarrheal sequelae caused by Escherichia coli O157:H7 infection in the gnotobiotic piglet model. Toxins 9:49.
  7. Schneider, L. G., T. J. Klopfenstein, Z. R. Stromberg, G. L. Lewis, G. E. Erickson, R. A. Moxley, and D. R. Smith. 2018. A randomized controlled trial to evaluate the effects of dietary fibre from distillers grains on enterohemorrhagic Escherichia coli detection from the rectoanal mucosa and hides of feedlot steers. Zoonoses and Public Health 65:124-133
  8. Stromberg, Z. R., G. L. Lewis, L. G. Schneider, G. E. Erickson, I. R. Patel, D. R. Smith, and R. A. Moxley. 2018. Culture-based quantification with molecular characterization of non-O157 and O157 enterohemorrhagic Escherichia coli isolates from rectoanal mucosal swabs of feedlot cattle. Foodborne Pathogens and Disease 15:26-32.
  9. Kittana, H., M. I. Quintero-Villegas, L. B. Bindels, J. C. Gomes-Neto, R. J. Schmaltz, R. R. Segura Munoz, E. A. Cody, R. A. Moxley, J. Hostetter, R. W. Hutkins, and A. E. Ramer-Tait. 2018. Galactooligosaccharide supplementation provides protection against Citrobacter rodentium infection but does not limit pathogen adherence. Microbiology 164:154-162.
  10. Lewis, G. L., Q. R. Jorgensen, J. D. Loy, and R. A. Moxley. 2018. Tellurite resistance in Shiga toxin-producing Escherichia coli. Current Microbiology 75:752-759.
  11. Schneider, L. G., G. L. Lewis, R. A. Moxley, and D. R. Smith. 2018. A four-season longitudinal study of enterohemorrhagic Escherichia coli in beef cow-calf herds in Mississippi and Nebraska. Zoonoses and Public Health 65:552-559.
  12. Schneider, L. G., Z. R. Stromberg, G. L. Lewis, R. A. Moxley, and D. R. Smith. 2018. Cross-sectional study to estimate the prevalence of enterohemorrhagic Escherichia coli on hides of market beef cows at harvest. Zoonoses and Public Health 65:625-636.
  13. Lu, T., H. Seo, R. A. Moxley, and W. Zhang. 2019. Mapping the neutralizing epitopes of F18 fimbrial adhesin subunit FedF of enterotoxigenic Escherichia coli (ETEC). Veterinary Microbiology 230:171-177.
  14. Lu, T., R. A. Moxley, and W. Zhang. 2019. Mapping the neutralizing epitopes of enterotoxigenic Escherichia coli (ETEC) K88 (F4) fimbrial adhesin and major subunit FaeG. Applied and Environmental Microbiology 85:e00329-19.
  15. Moxley, R. A., D. R. Smith, D. M. Grotelueschen, and T. Edwards. 2019. Investigation of congestive heart failure in beef cattle in a feedyard at a moderate altitude in western Nebraska. Journal of Veterinary Diagnostic Investigation 31:509-522.
  16. Moxley, R. A., T. W. Bargar, S. D. Kachman, D. R. Baker, and D. H. Francis. 2020. Intimate attachment of Escherichia coli O157:H7 to urinary bladder epithelium in the gnotobiotic piglet model. Microorganisms 8:263.
  17. Lu, T., R. A. Moxley, and W. Zhang. 2020. Application of a novel epitope and structure vaccinology-assisted fimbria-toxin multiepitope fusion antigen of enterotoxigenic Escherichia coli for multivalent vaccine development against porcine post-weaning diarrhea. Applied and Environmental Microbiology 86:e00274-20.
  18. Lewis, G. L., N. Cernicchiaro, and R. A. Moxley. 2020. Performance of chromogenic agar media for isolation of Shiga toxin-producing Escherichia coli from ground beef. Journal of Food Protection 83:1149-1154.
  19. Moxley R. A. 2021. (Editorial) Special Issue: Shiga toxin-producing Escherichia coli. Microorganisms 9:1.
  20. Jung, Y., A. C. S. Porto-Fett, S. Parveen, J. Meredith, B. A. Shoyer, E. Henry, Z. Trauger, L. E. Shane, M. Osoria, J. Schwarz, C. Rupert, B. Chapman, R. A. Moxley, and J. B. Luchansky. 2021. Recovery rate of cells of the seven regulated serogroups of Shiga toxin-producing Escherichia coli from raw veal cutlets, ground veal, and ground beef from retail stores in the mid-Atlantic region of the United States. Journal of Food Protection 84:220-232.
  21. Hinenoya, A., X.-P. Li, H. Wang, X. Zeng, O. Sahin, R. A. Moxley, C. M. Logue, B. Gillespie, S. Yamasaki, and J. Lin. 2021. Isolation and characterization of Escherichia albertii in poultry at the pre-harvest level. Zoonoses and Public Health 68:213-225.
  22. Lewis, G. L., N. Cernicchiaro, and R. A. Moxley. 2023. Effect of potassium tellurite concentration in a chromogenic agar medium on isolation of tellurite-resistant “Top Seven” Shiga toxin-producing Escherichia coli from ground beef. Journal of Food Protection 86:100017.
  23. Lewis, G. L., R. J. Fenton, E. N. Moriyama, J. D. Loy, and R. A. Moxley. 2023. Association of ISVsa3 with multidrug resistance in Salmonella enterica isolates from cattle (Bos taurus). Microorganisms 11:631.

Recent Book Chapters

  1. Moxley, R. A. 2022. Chapter 5, Family Enterobacteriaceae, In, McVey, D. S., M. Kennedy, and M. M. Chengappa, and R. Wilkes (eds.), Veterinary Microbiology, 4th Ed., Wiley-Blackwell, Hoboken, NJ, pp. 43-55.
  2. Moxley, R. A. 2022. Chapter 6, Enterobacteriaceae: Escherichia, In, McVey, D. S., M. Kennedy, and M. M. Chengappa, and R. Wilkes (eds.), Veterinary Microbiology, 4th Ed., Wiley-Blackwell, Hoboken, NJ, pp. 56-74.
  3. Moxley, R. A. 2022. Chapter 7, Enterobacteriaceae: Salmonella, In, McVey, D. S., M. Kennedy, and M. M. Chengappa, and R. Wilkes (eds.), Veterinary Microbiology, 4th Ed., Wiley-Blackwell, Hoboken, NJ, pp. 75-87.
  4. Moxley, R. A. 2022. Chapter 8, Yersiniaceae, In, McVey, D. S., M. Kennedy, and M. M. Chengappa, and R. Wilkes (eds.), Veterinary Microbiology, 4th Ed., Wiley-Blackwell, Hoboken, NJ, pp. 88-99.
  5. Moxley, R. A. 2022. Chapter 9, Enterobacteriaceae: Shigella, In, McVey, D. S., M. Kennedy, and M. M. Chengappa, and R. Wilkes (eds.), Veterinary Microbiology, 4th Ed., Wiley-Blackwell, Hoboken, NJ, pp. 100-107.


  • Shiga-toxigenic Escherichia coli (STEC) in the Beef Chain: Assessing and Mitigating the Risk by Translational Science, Education, and Outreach [USDA Coordinated Agricultural Project (STEC CAP)]. Moxley, R. A. USDA-NIFA-AFRI, Award No. 2012-68003-30155. $24,812,267, 1/1/2012 - 12/31/2019.
  • Genetic Analysis and Rapid Detection of Multidrug-Resistant Salmonella enterica Isolates from Cattle. Moxley, R. A., and J. D. Loy. Nebraska Beef Council and National Cattlemen’s Beef Association. $55,822, 10/1/2020 – 9/30/2021.
  • A Broadly Protective Vaccine against Porcine Post-Weaning Diarrhea (PWD). Zhang, W., R. A. Moxley, and N. Cernicchiaro. USDA-NIFA-AFRI, Animal Health and Disease, Area A1221, Award No. 2017-6701526632, $460,000 ($174,973 subaward), 5/15/2020 - 5/14/2025 (completion date extended due to institutional award transfer and COVID-19).

Awards and Honors

  • USDA-NIFA Partnership Award for Mission Integration, 2017 
  • Honorary Member, American College of Veterinary Microbiologists, 2019 
  • 2019 Best Manuscript Award, Journal of Veterinary Diagnostic Investigation, 2019
  • Excellence in Research Award, Gamma Sigma Delta (Honor Society of Agriculture), University of Nebraska-Lincoln Chapter, 2019


50% Research, 50% Teaching

Research Areas

  • Bacteriology
  • Pathology

Notable distinctions

  • Director, USDA Shiga toxin-producing Escherichia coli, Coordinated Agricultural Project (STEC-CAP), 2012-2019
  • President, Sigma Xi, University of Nebraska-Lincoln Chapter, 2013-2014
  • President, Conference of Research Workers in Animal Diseases, 2013
  • Charles Bessey Professor, University of Nebraska-Lincoln, 2016-present
  • Honorary Member, American College of Veterinary Microbiologists, 2019-present
  • Gamma Sigma Delta Excellence in Research Award, University of Nebraska-Lincoln, 2019
  • American Association of Veterinary Laboratory Diagnosticians Award for Best Journal of Veterinary Diagnostic Investigation manuscript, 2019
  • Scientist, National Institute for Antimicrobial Resistance Research and Education, 2020
  • Member (2020-present) and Chair (2021), Advisory Council, National Institute for Antimicrobial Resistance Research and Education
  • Fellow, National Strategic Research Institute, 2021-present