Faculty Interest

Barletta, R.G., rbarletta@unl.edu

Molecular genetics of bacterial pathogenesis and drug resistance, with emphasis of mycobactrial infections of humans and animals (tuberculosis and paratuberculosis).

Johne's disease, inflammatory bowel disease and Mycobacterium paratuberculosis. Chacon, O., Bermudez, L.E., Barletta, R.G. 2004. Annu Rev Microbiol 58:329-63.

List of PubMed-indexed publications

Brodersen, B.W., bbrodersen1@unl.edu

Further development of test methodologies for detection of cattle persistently infected with bovine viral diarrhea virus. Pathogenesis of bovine viral diarrhea virus infections.

Safety and efficacy of vaccination of seronegative bulls with modified-live, cytopathic bovine viral diarrhea viruses.  M. Daniel Givens, D.V.M, Ph.D; Kay P Riddell, DVM, MS; Yijing Zhang, BS; Patricia K Galik, MS; Paul H Walz,  DVM, PhD, DACVIM; Bruce Brodersen, DVM, PhD; Jason W Johnson, DVM; Thomas Passler, DVM; Phil Widel, DVM; Rob Tremblay, DVM, DVSc, DACVIM. Theriogenology. Accepted.

List of PubMed-indexed publications

Doster, A.R., adoster1@unl.edu

PRRS virus infection in swine and its effects on the host regarding variation in strains, host genetics, and latency. Additional studies are under way to study the effects of latency and reactivation of bovine herpesvirus 1 in cattle.Protection against Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection through passive transfer of PRRSV-neutralizing antibodies is dose dependent. Doster, A.R. 2007. Clin Vac Immunol 14:269-75.

List of PubMed-indexed publications

Griffin, D.D., dgriffin@gpvec.unl.edu

Interrelationships of factors affecting grass and feeder cattle production.

Assessing performance of feedlot operations using epidemiology. Corbin, M.J., Griffin, D. 2006. Vet Clin of North America 22:1:35-52.

List of PubMed-indexed publications

Jones, C., cjones2@unl.edu

Regulation of alpha-herpesvirus latency and neurovirulence, analysis of alpha-herpesvirus genes expressed during latency, innate immune response to virus infection, and regulation of apoptosis by herpesviruses.

A protein encoded by the bovine herpes virus 1 (BHV-1) latency related gene interacts with specific cellular regulatory proteins, including the CCAAT enhancer binding protein alpha (C/EBP-). Meyer, F., Perez, S., Geiser, V., Sintek, M., Inman, M., Jones, C. 2007. J Virol 81:59-67.

List of PubMed-indexed publications

Kammermann, John, jkammermann2@unl.edu

Macro and microstructure of bone and cartilage (both pathologic and normal) through immunohistochemical, biochemical, and histological analysis. Currently involves the integration of computer technology to enhance the teaching and study of veterinary gross anatomy.

Kammermann, JR, Kincaid SA, Rumph PF, Baird DK, and Visco DM, 1996. Tumor necrosis factor-α (TNF-α) in canine osteoarthritis: Immunolocalization of TNF-α, stromelysin, and TNF receptors in canine osteoarthritic cartilage. Osteroarthritis and Cartilage 4:23-34.

List of PubMed-indexed publications

Kelling, C.L., ckelling1@unl.edu

Pathogenesis and virulence of bovine viral diarrhea virus and bovine respiratory syncytial virus.

In vitro and vivo translational efficiencies of the 5' untranslated region from eight genotype 2 bovine viral diarrhea virus field isolates. Topliff, C.L., Chon, S.K., Donis, R.O., Eskridge, K.M., Kelling, C.L. 2005. Virology 331:349-356.

List of PubMed-indexed publications

Lou, M.F., mlou1@unl.edu

Biochemical mechanism of age-related cataract, the redox regulation and signal transduction in ocular tissues.

Control of PDGF-induced reactive oxygen species (ROS) generation and signal transduction in the human lens epithelial cells. Chen, C-W.K., Zhou, Y., Zhang, W., Lou, M.F. 2007. Molecular Vision 13:374-387.

List of PubMed-indexed publications

Moxley, R.A., rmoxley1@unl.edu

Pathogenesis of enterotoxigenic and enterohemorrhagic  Escherichia coli infections in swine and cattle.

Anti-capsular antibodies activate killing of Escherichia coli O8:K87 by the alternative complement pathway in porcine serum. Clark, N.M., Berberov, E.M., Wang, M., Moxley, R.A. 2006. Vet Immunol Immunopath 114:185-91.

List of PubMed-indexed publications

Osorio, F.A., fosorio1@unl.edu

Virulence and pathogenesis of two major viral agents that affect swine: Pseudorabies Virus (a herpesvirus) and Porcine Reproductive and Respiratory Syndrome Virus (an arterivirus, ssRNA+ genome).

Kwon, B. J., Ansari, I. H., Pattnaik, A. K., and Osorio, F. A. 2008. Identification of virulence determinants of Porcine Reproductive and Respiratory Syndrome virus through construction of chimeric clones. Virology 380: 371-37

List of PubMed-indexed publications

Pattnaik, A., apattnaik2@unl.edu

Molecular mechanisms of RNA virus transcription, replication, and assembly; viral pathogenesis; attenuated viruses and vaccines.

Visualization of intracellular transport of vesicular stomatitis virus nucleocapsids in living cells. Das, S.C., Nayak, D., Zhou, Y., Pattnaik, A.K. 2006. J Virol 80:6368-77.

List of PubMed-indexed publications

Reddy, Jay, nreddy2@unl.edu   

Cellular and molecular mechanisms of immune system activation and autoimmunity.

Myelin proteolipid protein-specific CD4+CD25+ regulatory cells mediate genetic resistance to experimental autoimmune encephalomyelitis. Reddy J., Illes Z., Zhang X., Encinas J., Pyrdol J., Nicholson L., Sobel R., Wucherpfennig K and Kuchroo V.  2004. Proc. Natl. Acad. Sci. 101: 15434.

List of publications can be found on his personal page

Rogers, D.G.

Diagnostic investigation, pathogenesis of bacterial diseases in livestock.

Henry E. Cerny, Douglas G. Rogers, Jeffrey T. Gray, David R. Smith, and Susanne Hinkley . 2006, Effects of Moraxella (Branhamella) ovis culture filtrates on bovine erythrocytes, peripheral blood mononuclear cells and corneal epithelial cells.. J. Clin. Microbiol 44(3):772-776. American Society for Microbiology . Washington, DC.

Sollars, Patricia, psollars2@unl.edu

Circadian rhythms, Circadian regulation of sleep, Seasonal affective disorder

List of PubMed-indexed publications

Somerville, G.A., gsomerville3@unl.edu

Elucidation of the mechanisms by which staphylococcal metabolism controls virulence and survival within a host.

M. R. Sadykov, M. E. Olson, S. Halouska, Y. Zhu, P. D. Fey, R. Powers, and G. A. Somerville. 2008. Tricarboxylic acid cycle dependent regulation of Staphylococcus epidermidis polysaccharide intercellular adhesin synthesis. J. Bact. 190:7621-7632.

List of PubMed-indexed publications

Steffen, D.J., dsteffen1@unl.edu

Pathology of genetic and infectious diseases.

Characterization of protection from systemic infection and disease by use of a modified-live noncytopathic bovine viral diarrhea virus type 1 vaccine in experimentally infected calves. Kelling, C.L., Hunsaker, B.D., Steffen, D.J., Topliff, C.L., Abdelmagid, O.Y., Eskridge, K.M. 2005. Am J Vet Res 66(10):1785-91.

List of PubMed-indexed publications